Posted by Jack
“Achillion Announces Updated Phase 2 Results for ACH-3102 Plus Ribavirin in Genotype 1b Treatment-Naive Hepatitis C Patients
6:13a ET April 23, 2013 (Benzinga)
Achillion Pharmaceuticals (NASDAQ: ACHN) today announced updated interim safety and efficacy results, including early sustained virologic response (SVR4) data, from the pilot Phase 2 trial evaluating once-daily ACH-3102 plus ribavirin (RBV) in treatment-naïve patients with genotype 1b, IL28B CC subtype, chronic hepatitis C virus (HCV) infection. All of the 8 patients enrolled in the trial completed 12 weeks of treatment with no virologic breakthrough observed. ACH-3102 also demonstrated continued declines in HCV RNA in the presence of up to six baseline mutations that are known to confer a high level of resistance to 1st generations NS5A inhibitors. ACH-3102 was deemed safe and well-tolerated with no significant adverse events reported. In all, 75% of patients (6 of 8) had HCV RNA < 25 IU/ml at the end of treatment and 63% (5 of 8) achieved early sustained virologic response 4 weeks (SVR4) after the completion of therapy.”
I’ve been following this stock for awhile and it’s been on a steady decline, down over 3% today and it looks like it could be close to a bottom. A lot is riding on their latest product, a treatment for hepetitis C. They just released promising results today. I’m surprised the stock has not shot up? This could a bonanza if tests continue to be positive. They are almost done with human testing and the goal is in sight. Stay tuned and maybe you better watch this stock…? Could be huge, IF they stay on track.
Jack, you’re not thinking it through.
Presuming their government subsidized research is successful, who’s going to pay the $100 a dose? Hep-C patients tend to be drug addicts, and uninsured.
So, us taxpayers subsidize the research, and then we pay for the meds … you get to collect dividends … and continue to weedle out of your tax obligations? Do that really sound sustainable?
Well Libby, no, I never quite saw it that way. But, you have made a fair number of broad assumptions that aren’t in evidence in any way shape or form, one of those assumption is I weedle out of my tax obligations. Not sure why you would say that? However, no weedling here. Rejoice in the knowledge that I pay a substantial part of my income in taxes and not all in income tax, but property tax, school bond tax, sewer tax, cable tax, phone tax, car tax (6 vehicles), luxury tax and a ton in sales tax. About 23% of my income goes to pay some sort of tax. Do I rate a pat on the wallet now?
Of course not Jack! You’re not paying a high enough tax rate on dividend income! And don’t forget they really want a tax on every transaction or trade!
I don’t know why our progressive friends don’t just admit that they want all of America (except themselves) placed into slavery. They want us to work, to invent and invest, but they want all of the fruits of our labors owned by the state.
Tina: “And don’t forget they really want a tax on every transaction or trade!”
You say that, but the link you provide to support that claim says it’s a tax on “most non-consumer trades,” not “every transaction or trade.” Either you’re really bad at reading comprehension, or you’re intentionally lying.
Also, it’s hilarious that you’re complaining about a tax on Wall Street trading that amounts to only three cents per every hundred dollars. “Won’t some1 plz think of the rich?! They r jus so oppressed!!!”
“I don’t know why our progressive friends don’t just admit that they want all of America (except themselves) placed into slavery.”
OK, I admit it! Every night I pray to the ghosts of Robert E. Lee and Karl Marx, and watch as they partake in an unholy union. I would have gotten away with it too, if it weren’t for vigilant patriots such as yourself, ensuring that no Wall Street trader has to live under the tyranny of paying a tax on his
hard-earned moneyreckless high-speed trading!“…assumptions that aren’t in evidence in any way shape or form, ….”
Jack, how is it, do you suppose, that medical costs have sky-rocketed, lo, these twenty, thirty years? Do you really think my scenario plays no part? Think again.
Libby, In 2009, there were an estimated 16,000 acute Hepatitis C virus infections reported in the United States. That’s a lot of sick people who are seeking help and a lot of medical dollars are already going for their treatment. However, it gets even worse, much worse. There are an estimated 3.2 million persons in the United States have chronic Hepatitis C virus infection. Most people do not know they are infected because they don’t look or feel sick, but 75%–85% of them will eventually get worse and show signs of chronic infection and they can spread the disease without knowing it.
I don’t know why you took an attitude with a private drug company, using private research dollars to develop a treatment for Hep-C? Your logic escapes me. Sure, some of your tax money may go for their treatment, but you’re already paying big time anyway, with a better program you could be paying a lot less and transmission would be substantially curtailed…what’s wrong with that? And what’s wrong with the company making a profit off their drug and investors getting a return on their investment? Sometimes Libby I think you don’t like our system…other times I’m sure of it. And you sure are showing much concern for seriously ill people either!
“I don’t know why our progressive friends don’t just admit that they want all of America (except themselves) placed into slavery.”
You know, this bears absolutely no objective relation to anything I said. This is prejudicial spouting and entirely nonsensical.
If you want scientific research subsidized, you support a healthy tax base.
If you want addicts to receive meds they can’t pay for, you support a healthy tax base.
I point out the incongruity of Jack’s position: benefiting from subsidized research to develope a drug there is little market for … and yet … expending vast effort and resources to avoid his tax obligations.
And you pipe up with “slavery”? That is not an argument. That is nonsense. Stop wasting everybody’s time.
“And you sure are showing much concern for seriously ill people either!”
I’m being devil’s advocate. 3.2 million really, actually, isn’t … and 16,000 positively isn’t … a lot of sick people in the great cosmic scheme of things, and once again … why should you reap dividends, when you won’t pay the taxes that engender the dividends?
I am waiting for you to address this issue.