Oldest Human DNA Found – 400,000 Years Old!

Posted by Jack

hominins235
See anyone familiar? They might be your ancestors. The oldest known human DNA found yet reveals human evolution was even more confusing than before thought, researchers say. The genetic material came from the bone of a hominin living in what is now the Sima de los Huesos in Northern Spain.

By Charles Q. Choi, LiveScience

The oldest known human DNA found yet reveals human evolution was even more confusing than thought, researchers say.

The DNA, which dates back some 400,000 years, may belong to an unknown human ancestor, say scientists. These new findings could shed light on a mysterious extinct branch of humanity known as Denisovans, who were close relatives of Neanderthals, scientists added.

Although modern humans are the only surviving human lineage, others once strode the Earth. These included Neanderthals, the closest extinct relatives of modern humans, and the relatively newfound Denisovans, who are thought to have lived in a vast expanse from Siberia to Southeast Asia. Research shows that the Denisovans shared a common origin with Neanderthals but were genetically distinct, with both apparently descending from a common ancestral group that had diverged earlier from the forerunners of modern humans. [See Images of Excavation & Mysterious ‘New Hominid’]

Genetic analysis suggests the ancestors of modern humans interbred with both these extinct lineages. Neanderthal DNA makes up 1 to 4 percent of modern Eurasian genomes, and Denisovan DNA makes up 4 to 6 percent of modern New Guinean and Bougainville Islander genomes in the Melanesian islands.

Pit of Bones

To discover more about human origins, researchers investigated a human thighbone unearthed in the Sima de los Huesos, or “Pit of Bones,” an underground cave in the Atapuerca Mountains in northern Spain. The bone is apparently 400,000 years old.

“This is the oldest human genetic material that has been sequenced so far,” said study lead author Matthias Meyer, a molecular biologist at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany. “This is really a breakthrough — we’d never have thought it possible two years ago that we could study the genetics of human fossils of this age.” Until now, the previous oldest human DNA known came from a 100,000-year-old Neanderthal from a cave in Belgium.

The Sima de los Huesos is about 100 feet (30 meters) below the surface at the bottom of a 42-foot (13-meter) vertical shaft. Archaeologists suggest the bones may have been washed down it by rain or floods, or that the bones were even intentionally buried there.

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The thighbone of the 400,000-year-old hominid from Sima de los Huesos, Spain.

This Pit of Bones has yielded fossils of at least 28 individuals, the world’s largest collection of human fossils dating from the Middle Pleistocene, about 125,000 to 780,000 years ago.

“This is a very interesting time range,” Meyer told LiveScience. “We think the ancestors of modern humans and Neanderthals diverged maybe some 500,000 years ago.” The oldest fossils of modern humans found yet date back to about 200,000 years ago.

Denisovan relative?

The researchers reconstructed a nearly complete genome of this fossil’s mitochondria — the powerhouses of the cell, which possess their own DNA and get passed down from the mother. The fossils unearthed at the site resembled Neanderthals, so researchers expected this mitochondrial DNA to be Neanderthal.

Surprisingly, the mitochondrial DNA reveals this fossil shared a common ancestor not with Neanderthals, but with Denisovans, splitting from them about 700,000 years ago. This is odd, since research currently suggests the Denisovans lived in eastern Asia, not in western Europe, where this fossil was uncovered. The only known Denisovan fossils so far are a finger bone and a molar found in Siberia. [Denisovan Gallery: Tracing the Genetics of Human Ancestors]

“This opens up completely new possibilities in our understanding of the evolution of modern humans, Neanderthals and Denisovans,” Meyer said.

The researchers suggest a number of possible explanations for these findings. First, this specimen may have been closely related to the ancestors of Denisovans. However, this seems unlikely, since the presence of Denisovans in western Europe would suggest an extensive overlap of territory with Neanderthal ancestors, raising the question of how both groups could diverge genetically while overlapping in range. Moreover, the one known Denisovan tooth is significantly different from teeth seen at the Pit of Bones.

Second, the Sima de los Huesos humans may be related to the ancestors of both Neanderthals and Denisovans. The researchers consider this plausible given the fossil’s age, but they would then have to explain how two very different mitochondrial DNA lineages stemmed from one group, one leading to Denisovans, the other to Neanderthals.

Third, the humans found at the Sima de los Huesos may be a lineage distinct from both Neanderthals and Denisovans that later perhaps contributed mitochondrial DNA to Denisovans. However, this suggests this group was somehow both distinct from Neanderthals but also independently evolved several Neanderthal-like skeletal features.

Fourth, the investigators suggest a currently unknown human lineage brought Denisovan-like mitochondrial DNA into the Pit of Bones region, and possibly also to the Denisovans in Asia.

“The story of human evolution is not as simple as we would have liked to think,” Meyer said. “This result is a big question mark. In some sense, we know less about the origins of Neanderthals and Denisovans than we knew before.”

The scientists now hope to learn more about these fossils by retrieving DNA from their cell nuclei, not their mitochondria. However, this will be a huge challenge — the researchers needed almost 2 grams of bone to analyze mitochondrial DNA, which outnumbers nuclear DNA by several hundred times within the cell.

The scientists detailed their findings in the Dec. 5 issue of the journal Nature.

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10 Responses to Oldest Human DNA Found – 400,000 Years Old!

  1. Tina says:

    Offered for consideration to those with an open mind and a bit of curiosity who are willing to question “settled” science:

    ICR.Org

  2. Pie Guevara says:

    The limitations of carbon dating are well known. Other methods are deployed to estimate the age of fossils from all earth ages, including where carbon dating is relatively reliable.

    http://paleo.cc/kpaleo/fossdate.htm

    “But, beloved, be not ignorant of this one thing, that one day is with the Lord as a thousand years, and a thousand years as one day.”

    Peter 3:8 King James Version

  3. Dewey says:

    “When fascism comes to America, it will be wrapped in the flag and carrying the cross.” This insightful quote is from a book written in 1935 by Sinclair Lewis

  4. Tina says:

    Thoughts on fascism from Austrian economist Ludwig von Mises published in, “Planned Chao,” 1947:

    “There were nowhere more docile disciples of Lenin, Trotsky, and Stalin than the Nazis…. They imported from Russia: the one-party system and the preeminence of this party in political life; the paramount position assigned to the secret police; the concentration camps; the administrative execution or imprisonment of all opponents; the extermination of the families of suspects and of exiles; the method of propaganda,” and many other techniques besides.”

    Fascist thinking is common in American liberal progressives. Consider this excerpt from “Financial Fascism,” by Richard Rahn, Cato:

    The “Dodd financial reform” bill being considered by the Senate will make it illegal for 99.6 percent of the population to invest in needed new and promising start-up companies while at the same time ensuring that the 33 largest banks, which control 92 percent of all bank assets, will be required to purchase more federal government debt before giving loans to businesses and individuals. Quite simply, the government is continuing to practice financial fascism.

    The new health care bill will require us to buy specified health insurance, whether it is appropriate for us or not. Government-run ads encourage people to buy tickets in government-run lotteries, where the expected value can be less than one-sixth of the ticket price. Yet the new financial reform bill will make it illegal to invest in a new venture or start-up company for anyone who does not have a liquid net worth of $2.2 million or an annual income of roughly $450,000 if single or $675,000 if married — which rules out all but fewer than 1 percent of the population. If this passes and is signed into law, Congress and the president will be saying to the American people, “Ninety-nine-plus percent of you are too stupid to know how to invest your own money.”

    Quotes from Jonah Goldberg, author of “Liberal Fascism: The Secret History of the American Left from Mussolini to the Politics of Meaning”:

    “If there is ever a fascist takeover in America, it will come not in the form of storm troopers kicking down doors but with lawyers and social workers saying. “I’m from the government and I’m here to help.”

    “If you think shrinking government and getting it less involved in your life is a hallmark of tyranny it is only because you are either grotesquely ignorant or because you subscribe to a statist ideology that believes the expansion of the state is the expansion of liberty.”

    “Hence the great irony: Hayek, one of the greatest champions of individual liberty and economic freedom the world has ever known, believed that knowledge was communal. Dewey, the champion of socialism and collectivism, believed that knowledge was individual. Hayek’s is a philosophy that treats individuals as the best judges of their own self-interests, which in turn yield staggering communal cooperation. Dewey’s was the philosophy of a giant, Monty Pythonesque crowd shouting on cue: “We’re All Individuals!”

    And then there is Marx”

    “The last capitalist we hang shall be the one who sold us the rope.”

    “From each according to his abilities, to each according to his needs.”

    Evil always stays in darkness and cannot stand the light of truth, hence, fascism, as well as communism, have “come to America wrapped in the flag and carrying the cross” simply because it is covert, it is insidious…and extremely patient.

  5. Peggy says:

    The Horrific Story That Prompted David Horowitz’s Conservative Transformation:

    “David Horowitz, author of The Black Book of the American Left and the founder and president of the David Horowitz Freedom Center, has spoken at length about how he was raised by “card-carrying communists” who always “described themselves as progressives.” He followed in their footsteps, becoming one of the founders of the New Left in 1960′s, which he described as an organization “formed by children of communists who wanted to get away from the taint that Stalin had put on (communism), and revive the vision.”

    Horowitz warned that while there are horrifically violent elements to the left, like the Black Panther Party, “you should not think that the bad forces are going to appear with black hats and it’ll be obvious who they are.”

    Many, like his parents, he said, are “well-meaninged people” who will “speak with humanitarian tones,” but just believe “the ends justify the means.”

    “When Lenin set out to transform, fundamentally transform Russia, he didn’t say he was going to kill 40 million people, create famines and concentration camps called gulags,” Horowitz remarked. “He said he was going to give them bread, land, and peace.”

    Horowitz also warned that “you can’t understand what’s going on” in American politics today without realizing the history behind it – the world he was raised in.

    “It’s the same people and the same vision. Barack Obama, Valerie Jarret, who’s his key advisor, and David Axelrod, who’s his political strategist — all of them were born into the same communist left that I was. They grew up in it; they were trained in it; they were trained to what I call the neo-communist new left, and they’ve never left it.

    Horowitz said he knows they still maintain such a worldview because “if you understand that you belong to a movement that has agendas which are evil and destructive … the first thing you want to do if you’re still political is to repudiate it and to warn others against it. And of course, Obama, Jarrett, and David Axelrod are comfortable parts of this left … They’ve carried on the agendas. That’s why the country is suffering the way it is.”

    http://www.theblaze.com/stories/2013/12/03/the-horrific-story-that-prompted-david-horowitz-conservative-transformation/

  6. Tina says:

    Americans should listen to the man, he knows what he’s talking about. The average American that hears the smooth rhetoric, the promise of income equality and fundamental fairness, have no idea what is actually going to be the effect in their lives from the laws that are being written. They have no idea that those radicals that have taken over the Democrat Party have little affinity for the principles of freedom, property rights, speech rights…the right to pursue happiness. They are about central planning and control by the elites of government.

  7. Pie Guevara says:

    Re #3 Dewey :

    Sinclair Lewis, like Al Gore, was an overrated narcissistic boob. He was obviously suffering deeply from his long term alcoholism when he wrote “When fascism comes to America, it will be wrapped in the flag and carrying the cross.” The real world events that came to pass bear that out, but I wouldn’t expect an ignoramus like Dewey to even recognize that.

    My hunch is that Dewey has never actually read a single Sinclair Lewis novel. He just grabbed a stupid quote he thinks clever and passes for intelligence.

  8. Tina says:

    And appropriate to the creation…what about the flood?

  9. Tina says:

    Oops…wrong observation. Sorry guys. Pie is astute….in stereo!

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